SciELO - Scientific Electronic Library Online

 
vol.35 número2Determinación de trazas de lidocaína y epinefrina en el proceso de limpieza posterior a la fabricación de carpulesEvaluación de reactivos cubanos elaborados para el diagnóstico rápido de Haemophilus influenzae tipo B índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Artigo

Indicadores

  • Não possue artigos citadosCitado por SciELO

Links relacionados

  • Não possue artigos similaresSimilares em SciELO

Compartilhar


Revista Cubana de Farmacia

versão On-line ISSN 1561-2988

Resumo

SORDO MARTINEZ, Liset; RODRIGUEZ DE LA ROSA, Ángel Rafael  e  CRUZ MORALES, Jorge. Validación de la técnica para la determinación cuantitativa de cefotaxima sódica por Clar. Rev Cubana Farm [online]. 2001, vol.35, n.2, pp. 104-108. ISSN 1561-2988.

The validation of the high-performance liquid chromatography method for the quantitative determination of cefotaxime sodium, a well-known antibacterial compound, was carried out. Taking into account that this method is rated as a method for quantitative determination of the active ingredient or main compound in formulations or raw materials, the following parameters were evaluated: specificity, linearity, precision and accuracy. The results showed that the technique is reliable since it allowed the determination of the studied compound in the face of synthesis impurities and degradation products. Also, the statistical processing of the results revealed the linearity, precision and accuracy of the method.

Palavras-chave : CEFOTAXIME [analysis]; CEFOTAXIME [pharmacology]; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHEMISTRY PHAR-MACEUTICAL; TECHNOLOGY, PHARMACEUTICAL.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License