Resumo

GATO DEL MONTE, Armando; GONZALEZ VILLAZON, Ania  e  PARDO RUIZ, Zenia. Technological development of zinc sulphate 5 mg/mL intravenous infusion. Rev Cubana Farm [online]. 2005, vol.39, n.2, pp. 1-1. ISSN 1561-2988.

A formulation of zinc sulphate 5 mg/mL for  intravenous infusion was developed. It met the quality specifications of the USP 26, and it underwent  the study of physical, chemical, microbiological and biological stability of the solution stored in neutral glass flasks  of 5 ml of hydrolitic quality I. The product was exposed to heat for 90 days and to heat and the action of light for a period of  180 days, as well as to a shelf  life under normal conditions of room temperature. It was proved the effectivity of  the antimicrobial preservatives present in the formulation. According  to the conducted studies, it was determined that the solution is stable for more than 18 months stored at  room temperature.

Palavras-chave : Zinc sulphate; stability; parenteral administration..

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