Resumo

VAZQUEZ VIGOA, Alfredo; LLORENS NUNEZ, Martha  e  CRUZ ALVAREZ, Nélida María. Hipertensión arterial: Aspectos fisiopatológicos. Rev cubana med [online]. 1996, vol.35, n.3, pp. 176-182. ISSN 1561-302X.

The physiopathological aspects involved in the genesis of the hypertensive disease were revised in order to up-date the understanding regarding the mechanisms which generate high blood pressure. Emphasis was made in the increased peripheral resistance, the disorders of sodium excretion and on alterations regarding the sodium transport through the membrane. In addition, new theories about certain vasoactive substances recently found, capable of increasing the vascular tone such as endotelin, are also pointed out. Local or self endocrine systems of renin/angiotensin/aldosterone were found to be related to arterial hypertension. The authors concluded that certain humoral alterations capable of perpetuating the elevated arterial pressure are superimposed over the polygenic sustrate of hypertension.

Palavras-chave : HYPERTENSION [physiopathology]; HYPERTENSION [etiology].