Resumo

RUBIO GONZALEZ, Tamara  e  VERDECIA JARQUE, Manuel. Prion diseases. MEDISAN [online]. 2009, vol.13, n.4, pp. 0-0. ISSN 1029-3019.

Prion diseases are neurodegenerative processes occurred by aberrant metabolism of a prion protein that affect humans and animals during a long period of incubation, with transmissible character and fatal clinical course. Among their clinical manifestations are insanity, ataxia, insomnia, and paraplegias, paresthesias and abnormal behaviors. The main patological finding is the spongiform aspect of the infected animal and human brain caused by accumulation of prion proteins in the neurons, where they form amyloid plaques. There is not treatment that cures, improves or controls symptoms and signs of these conditions, therefore several questions and different opinions in this regard raise in the world scientific community that justified to continue arguing in this paper.

Palavras-chave : PRION DISEASES,PRION DISEASES [history]; PRION DISEASES [transmission]; PRION DISEASES [diagnosis]; PRION DISEASES [etiology]; CREUTZFELDT-JAKOB SYNDROME; KURU; GERSTMANN STRAUSSLER-SCHEINKER DISEASE; INSOMNIA, FATAL FAMILIAL.

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