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Revista Cubana de Cirugía

versión impresa ISSN 0034-7493versión On-line ISSN 1561-2945

Resumen

MARTINEZ BLANCO, Carlos A; LLORENS FIGUEROA, José A  y  PEREZ NELLAR, Jesús. Timomas y miastenia gravis: Supervivencia y factores pronósticos, catorce años de experiencia. Rev Cubana Cir [online]. 2003, vol.42, n.3. ISSN 0034-7493.

This paper presents an analytical cohort study to evaluate prognostic factors in 34 patients with thymona and myasthemia gravis whom thymectomy from January 1984 to December 1998. Twenty two were females and 12 males aged 49,7 years of age as average. According to Masaoka´s clinical classification, 14 patients were at stage I; two at stage II, 12 at stage III and 6 at stage IV. From the histological viewpoint, 17 were mixed thymona, 9 cortical thymonas, 5 medullar thymonas and 3 well-differentiated thymic carcinomas. According to Osswerman´s classification, 5 patients were included in group IIa, 23 in group IIb and 6 in group IV. The access pathway was median sternotomy. Remission index of myasthemic symptoms after a year was 53.1%. there were 3 deaths in the postoperative period and 7 died later. Cortical thymona and in general, invasive tumors showed the worst results. The most related factors to prognosis because of their influence over the disease-free interval and the long term survival were the clinical staging of tumor, the hystic type and the type of myasthemia

Palabras clave : THYMOMA [diagnosis]; MYASTHENIA GRAVIS [diagnosis]; THYMECTOMY [methods]; SURVIVAL RATE; PROGNOSIS.

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