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Revista Cubana de Cirugía

versión impresa ISSN 0034-7493versión On-line ISSN 1561-2945

Resumen

VILLAR INCLAN, Alejandro. Angiogenic therapy in the ischemic cardiopathy treatment. Rev Cubana Cir [online]. 2007, vol.46, n.3. ISSN 0034-7493.

The history of the use of growth factors and the concepts of angiogenesis, arteriogenesis and vasculogenesis were presented in this paper. The different growth factors that are known so far were stated, making emphasis on the most used (vascular endothelial and fibroblast growth factors). The various ways of application and of administration proteic or genic) were analyzed. An account of several preclinical and clinical studies using these growth factors for ischemic cardiopathy treatment were made. The various studies contributed information on the possible complications of the use of these factors; conclusions were drawn and recommendations were made

Palabras clave : growth factors; angiogenesis; vascular endothelial growth factor.

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