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Revista Cubana de Estomatología

versión impresa ISSN 0034-7507


CANTIN, Mario  y  SANDOVAL M, Catherine. Hypodontia and accessory navicular bone: an interesting syndromic association. Rev Cubana Estomatol [online]. 2012, vol.49, n.3, pp.242-250. ISSN 0034-7507.

Teeth are developed from many interactions between oral epithelium and mesenchymal cells. A number of genes are involved in tooth development, as well as in other organs, and upper and lower limbs. PAX9, a member of the transcriptional factor family, is one of the main drivers of this development, playing a key role in dental hypodontia and malformations in the lower limb bones. The aim of this report was to present the association between hypodontia and the accessory navicular bone based on a case report. This is a 18 years old female patient, who attended a dental clinic because she had acute pain in the 3.6 tooth and also pain on the left foot's inner area. The radiographic examination showed loss of the teeth 1.7, 2.7, 2.8, 3.8 and 4.8; and the presence of an accessory navicular bone in the left foot. It is interesting to suggest that this rare association, with clear dominant autosomal inheritance, might exist; since the dental agenesis and the presence of accessory navicular bone have similar prevalence, which could point to a new syndromic association probably related to the lack of PAX9.

Palabras clave : hypodontia; accessory navicular bone; PAX9; syndrome.

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