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Revista Cubana de Estomatología
versión On-line ISSN 1561-297X
Resumen
SANCHEZ BALLENA, Sally Thressy; ELIAS PODESTA, Mario César; ARELLANO SACRAMENTO, César y DIEGUEZ PEREZ, Montserrat. In vitro antibacterial activity of fluoride-free toothpastes against Streptococcus mutans strains. Rev Cubana Estomatol [online]. 2019, vol.56, n.3 Epub 15-Oct-2019. ISSN 1561-297X.
Introduction:
Toothpastes with active ingredients prevent dental caries in children.
Objective:
Determine the in vitro antibacterial activity of three fluoride-free toothpastes and two control solutions against standard Streptococccus mutans strains.
Methods:
A prospective cross-sectional experimental double-blind study was conducted. Trypticase soy agar was used applying the diffusion method at 37 °C for 24 h. The size of the growth inhibition haloes of each group was examined. Data analysis was based on SPSS15 software, using Shapiro-Wilk Gaussian distribution corroboration statistical tests, and the Kruskal-Wallis and Mann-Whitney tests.
Results:
Inhibition diameter was 26.69 mm (± 1.85) for 0.12 % chlorhexidine gluconate, 6 mm (± 0) for distilled water, and 6 mm (± 0) and 22.93 mm (± 3.39) for the toothpastes. Comparison of the diameters obtained by the action of 0.12 % chlorhexidine gluconate and distilled water with the fluoride-free toothpastes revealed statistically significant differences in only one of the cases (p< 0.05).
Conclusions:
Not all the baby toothpastes studied display antibacterial activity against the Streptococcus mutans strain ATCC 25175.
Palabras clave : toothpastes; antibacterial agents; Streptococcus mutans.