Abstract

LORENZO, María de los Ángeles; SERRATE, María Antonia; ARANGO, Ramón  and  PEREZ, Isabel. Desarrollo tecnológico de la suspensión oral de fenoximetilpenicilina 125 mg. Rev Cubana Farm [online]. 1997, vol.31, n.2, pp.81-85. ISSN 0034-7515.

The technological development of an oral formulation containing 125 mg of phenoxymethylpenicillin oral suspension for pediatric use is described. The formulation was obtained by a dryness procedure which is initiated mixing the active ingredient with flavours, stabilizings, edulcorates and lubricants until attaining a stable product having the characteristics which make the product being adequate for being used. The stability of the end product was studied from the technological and chemical point of view with satisfactory results. The drug produced complies with the most current requirements for its commercialization and forms part of the stable stock of "8 de Marzo" Pharmaceutical Enterprice.

Keywords : TECHNOLOGICAL DEVELOPMENT; PENICILLIN V; DRUG STABILITY; SUSPENSIONS; CHEMISTRY; PHARMACEUTICAL; DRUG COMPUNDING.