Abstract

LICEA TORNES, María Victoria; BADIA LLERENA, Mario  and  BORGES LEGRA, Concepción. Conservación de soluciones de referencia de ácido úrico. Rev Cubana Farm [online]. 1997, vol.31, n.2, pp.102-106. ISSN 0034-7515.

Different preservative agents were studied in order to select the one which may provide a greater time of useful life to reference solutions of uric acid. Stability of solutions in a rank of concentrations from 2 to 10 mg/dL (199-595F mol/L) was investigated keeping them under different conditions of storage: 2-8 EC, room temperature and 37 EC. The best results were observed when using thimerosal as a preservative agent since the correlation coeficient obtained by the analysis of linear regression was found to be higher than 0.9980 during 1 year for the solutions stored at 2-8 EC.

Keywords : URIC ACID; REFERENCE STANDARDS; SOLUTIONS; DRUG STABILITY; THIMEROSAL; STREPTOMYCIN; REAGENTS KITS, DIAGNOSTIC; SPECTROPHOTOMETRY.