Abstract

RODRIGUEZ RIERA, Zalua; XUAREZ MARILL, Lisbet  and  FERNANDEZ FALCON, Carlota A. Centro de química farmacéutica tiazolidinadionas: una nueva familia de hipoglicemiantes orales. Rev Cubana Farm [online]. 1997, vol.31, n.2, pp.138-144. ISSN 0034-7515.

A bibliographic review of a new series of compunds known as thiazolidinediones is made from a study of the most current and up-dated literature. Databases such as MEDLINE (1989-8/96), Excerpta Medica (1990-7/96), Predicast (1992-6/96), Medical Research Division (1991) and Life Science (1993-95) were consulted. Results obtained from preclinical and clinical trials of the derivates of this family known up to the present, are reported.

Keywords : THIAZOLES [pharmacology]; INSULIN [physiology]; HY-PERGLYCEMIA [physiopathology]; HYPERINSULINISM [physiopathology]; HYPERTRIGLICERIDEMIA [physiopathology]; DIABETES MELLITUS; NON-INSULIN-DEPENDENT; GLUCOSE TOLERANCE TEST; DISEASE MODELS, ANIMALS.