Abstract

PADRON YAQUIS, Alejandro S; FERNANDEZ NIEVES, Marjorie; MARTINEZ MIRANDA, Lisette  and  IZQUIERDO LOZANO, Julio C. Método analítico para la determinación de protirelina por cromatografía líquida de alta resolución. Rev Cubana Farm [online]. 1998, vol.32, n.2, pp.93-98. ISSN 0034-7515.

An analytical for the quality control and stability study of injectable protirelin was developed. The analysis was made by high pressure liquid chromatography with the utilization of an isocratic system of phosphate-methanol buffer (85:15) as a mobile phase and a Lichrosorb RP-18 column of 250 x 4 mm of 5 mm and ultraviolet detection at a wave length of 210 nm. The analytical method proved to be lineal, precise, accurate and specific in the range of studied concentrations.

Keywords : PROTIRELIN [analysis]; CROMATOGRAPHY, HIGH PRESSURE LIQUID [methods]; DRUG QUALITY; DRUG STABILITY.

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