Abstract

CAMERO SANTIESTEBAN, Amador Alberto et al. Composición de Inmunoglobulinas en la Inmunoglobulina Humana Antimeningocócica. Rev Cubana Farm [online]. 1998, vol.32, n.3, pp.151-156. ISSN 0034-7515.

IgG, IgA and IgM concentrations were estimated by turbidimetry, IgE was quantified aided by UMELISA-IgE from SUMA and the composition of IgG-specific subclasses to B meningococcal proteins was studied by means of an inmunoenzime procedure. It was found that IgG concentrations amounted to 47.98; 47.80 and 48.10 g/L, the IgA content was lower than or equal to 0.50 g/L IgM concentration was 0,25 g/L approximately and IgE levels exceeded 200 UI/mL. It is considered that there are IgG antibodies in the 4 IgG subclasses of which IgG1 is the predominant. An increased presence of IgG1 could be associated to a higher value of specific activity.

Keywords : NEISSERIA MENINGITIDIS [inmunology]; ANTIBODIES, BACTERIAL [analysis]; IGG [analysis]; IGA [analysis]; IGM [analysis]; NEPHELOMETRY AND TURBIDIMETRY [methods]; ENZYME LINKED INMUNOSORBENT ASSAY [methods].

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