Abstract

SUAREZ PEREZ, Yania et al. Estabilidad de los supositorios de quitina. Rev Cubana Farm [online]. 2000, vol.34, n.2, pp.100-107. ISSN 0034-7515.

Chitin suppositories are a new option in anorectal threapeutics, whose stability should be evaluated. The behaviour of 3 lots of suppositories made at a pilot scale and stored at 3 different temperatures by a period of 2 years was analyzed. Periodical checkings of the organoleptic properties, of the weight and liquefaction time parameters, as well as of the content of chitin were carried out by combining a gravimetric technique and infrared spectroscopy . The stability was investigated from the microbiological point of view by a differential count. The results were statisfactory for each evaluated parameter, since they were still within the limits for each of the assayed storage temperatures 2 years later.

Keywords : CHITIN [analysis]; SUPPOSITORIES; DRUG STABILITY; DRUG STORAGE.

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