Resumen

VEGA MONTALVO, Raiza  y  ALVAREZ FONG, Mayleng. Irritación ocular: Modelos alternativos. Rev Cubana Farm [online]. 2001, vol.35, n.3, pp. 211-218. ISSN 1561-2988.

The eye may be accidentally damaged by many products of daily use. To guarantee the consumers’ safety it is necessary to estimate the eye irritation potential of these chemical substances. This estimation is based on the results obtained in the Draize rabbit eye irritation test. However, the advances attained in the development of in vitro toxicology have allowed the use of some alternatives to evaluate the ocular risk. Therefore, a review is made on the different alternative methods available up to now that make possible the evaluation in one way or another of the toxic effects at the ocular level.

Palabras clave : IRRITANTS [toxicity]; COSMETICS [toxicity]; EYE [injuries]; RABBITS; DRUG EVALUATION; ANIMALS, LABORATORY.

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