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Revista Cubana de Farmacia
versão impressa ISSN 0034-7515versão On-line ISSN 1561-2988
Resumo
DIAZ POLANCO, Iverlis et al. Reformulation of chlorpromazine hydrochloride tablets 25 mg Reformulation of chlorpromazine hydrochloride tablets 25 mg. Rev Cubana Farm [online]. 2005, vol.39, n.1, pp.1-1. ISSN 0034-7515.
The reformulation of chlorpromazine hydrochloride 25 mg in the form of coated tablets was carried out. The technological process was designed from the making of the nuclei to the coating formulation in aqueous system that is feasible for its introduction at a pilot scale. The tablets obtained have a physical and chemical stability in the course of time and keep its potency within the therapeutic limits for 2 years.
Palavras-chave : Chlorpromazine; tablets; reformulation.