Revista Cubana de Farmacia
On-line version ISSN 1561-2988
GARCIA PENA, Caridad Margarita et al. Validation of the analytical methods for the quality control and stability study of salbutamol 0.5 % in nebulizing solution. Rev Cubana Farm [online]. 2005, vol.39, n.2, pp. 1-1. ISSN 1561-2988.
Two analytical methods were validated by spectrophotometry and high performance liquid chromatography for the quality control and the stability study, respectively, in the nebulizing solution of salbutamol 0.5 %. In the validation, there were evaluated the specificity parameters for these ends, lineality system, exactness and accuracy, which was expressed in its 2 ways: repeatability and intermediate precision. The analytical methods proved to be specific, lineal, accurate and exact in the interval of studied concentrations.
Keywords : Salbutamol; spectrophotometry; high performance liquid chromatography; quality control; stability study.