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Revista Cubana de Farmacia
versão impressa ISSN 0034-7515versão On-line ISSN 1561-2988
Resumo
RODRIGUEZ CHANFRAU, Jorge E. et al. Study of compared bioavailability of Calcidol Ò tablets at unique doses in healthy volunteers. Rev Cubana Farm [online]. 2007, vol.41, n.1. ISSN 0034-7515.
A clinical trial was made in healthy volunteers to evaluate the bioavailability of CalcidolÒ chewing tablets, compared to Calcium Carbonate 500 mg tablets. The results showed that the calcium urine concentrations obtained with both treatments were similar (188.47 ± 74.40 for CalcidolÒ versus 181.95 ± 86.33 for Calcium Carbonate, p= 0.1557). These results corroborate that both drugs present the same bioavailability.
Palavras-chave : Bioavailability; calcium carbonate; Calcidol.