Revista Cubana de Farmacia
versión On-line ISSN 1561-2988
DIAZ MATO, Ivette; CHAO CARDESO, Ashley Lázaro; JIMENEZ LOPEZ, Giset y LOPEZ VALDES, Yanet. Characterization of adverse events associated with vaccines immunizing against infectious diseases. 2006-2007. Rev Cubana Farm [online]. 2010, vol.44, n.3, pp. 325-335. ISSN 1561-2988.
A descriptive, transversal and retrospective study was conducted to characterize the adverse events temporarily associated with vaccines used in prevention and control of infectious diseases and that were notified to National Coordinator Unit of Pharmacosurveillance between the 2006-2007 years. Its behavior was determined according to the age, sex, notification origin, reporting staff, location and severity. Also, it was possible to identify the leading events reported and the vaccines involved in its appearance. Fever accounted for the 60 % of total of reported events. These latter were distributed equally between both sexes where the infants were the most affected (46.8 %).Report from Health Primary Care report was the more significant with 812 notifications. The most reports came from physicians (36 %). The behavior as regards severity was not different from that reported in literature, since fortunately there was predominance of slight events (66.4 %). However, contrary to expected, the systemic events had the greatest amount (80.2 %). pentavalent vaccine was related to 29.6 % of adverse events temporarily associated with vaccination.
Palabras llave : Adverse event; vaccines; infectious diseases; Pharmacosurveillance.