Abstract

ALONSO CARBONELL, Liuba; GARCIA MILIAN, Ana Julia; LOPEZ PUIG, Pedro  and  YERA ALOS, Isis. Comparison of the acceptability of two propellants from Salbutamol spray: Ciudad de La Habana during January-March, 2009. Rev Cubana Farm [online]. 2010, vol.44, n.3, pp.336-345. ISSN 0034-7515.

The change of propellant in spray Salbutamol formula by other of the ozone layer requires of evidences justifying its acceptability in population exposed to it. The aim of present study in Ciudad de La Habana was to assess and to compare the acceptability of Ventolin as an ecological propellant and the Cuban spray Salbutamol, after an educational intervention. The 841 patients included were distributed proportionally to inscribed figure for spray Salbutlamol in each (municipal weighting according to above figure). Patient's selection was made by thing fit for total of inscribed in each municipal drugstore. Most of person polled is satisfied with the size, the packing shape and the mouthpiece. The Ventolin's flavor and presentation were considered as pleasant but not much that of Salbutamol. The symptoms control was similar for both groups of patients. There were not significant differences in acceptability of both pharmaceutical products despite it Ventolin was slightly favored. These results support the introduction of Tetrafluoretane specifically the HCF 134 in the manufacture of spray Salbutamol since the acceptability level of Ventolin with this propellant is similar to that found for spray Salbutamol produced and marketed nowadays in Cuba.

Keywords : Asthma; Salbutamol; acceptability.

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