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Revista Cubana de Medicina
versión impresa ISSN 0034-7523versión On-line ISSN 1561-302X
Resumen
LLIBRE RODRIGUEZ, Juan de J. y GUERRA HERNANDEZ, Milagros A.. Enfermedad de Alzheimer: Situación actual y estrategias terapéuticas. Rev cubana med [online]. 1999, vol.38, n.2, pp.134-142. ISSN 0034-7523.
The most updated concepts of Alzheimer disease epidemiology and impact worldwide were reviewed. Ptential biological markers were described particularly hippocampal formation atrophy, presence of Tau protein and amyloid beta in cerebrospinal fluid, apoliprotein E4 genotype carrier and Alpha 2 macroglobulin. A diagnostic sequence was suggested to study patients with cognitive disorders, and also reference was made to present therapeutical strategies in treating cognitive and behavioral manifestations of this disease.
Palabras clave : ALZHEIMER DISEASE [epidemiology]; AMYLOID BETA PROTEIN [cerebrospinal fluid]; BIOLOGICAL MARKERS.