Resumo

GONZALEZ DEL VALLE GONZALEZ, Zulema et al. Síndrome de linfohistiocitosis hemofagocítica: a propósito de un caso. Rev cubana med [online]. 2003, vol.42, n.4. ISSN 0034-7523.

The hemophagocytic lymphohistiocytosis syndrome (HLH), though unfrequent in clinical practice, is of extraordinary interest due to its aggressive behavior and poor prognosis. The objective of this paper was to expose, starting from the experience derived from the observation of a case, the fundamental clinical characteristics: anemia, thrombocytopenia and neutropenia together with fever and splenomegaly. The causes that may produce such syndromes and lymphomas, as it occurred in this case, were discussed. It was concluded that the HLH is an specific entity and that a thorough search from the etiological point of view is needed to determine its cause. It was stressed that this case was secondary to a highly malignant non-Hodgking extranodal T cell lymphoma with renal taking leading to the death of the female patient in a short period of time.

Palavras-chave : HISTIOCYTOSIS, NON-LANGERHANS-CELL [etiology]; HISTIOCYTOSIS, NON-LANGERHANS-CELL [mortality]; LYMPHOMA, NON HODGKIN; ANEMIA; NEUTROPENIA; THROMBOCYTOPENIA; SPLENOMEGALY.