Resumen

VAZQUEZ SEISDEDOS, Carlos Román; MALLEUVE PALANCAR, José Ramón  y  PALLAS ARENY, Ramón. Cuantificación de la variabilidad de la repolarización ventricular en pacientes con cardiopatía isquémica. Rev cubana med [online]. 2003, vol.42, n.5. ISSN 0034-7523.

We propose the standard deviation ratio index (DERI) to quantify ventricular repolarization variability (VRV). This new index takes into account the changes in the fast and slow components of the RR, RTm (from R peak to T peak) and RTe (from R peak to T end) cardiac intervals. DERI has been evaluated in 20 healthy subjects, 12 subjects with coronary artery disease (CAD) and 13 subjects with acute myocardial infarction (AMI). The DERI index is lower in healthy subjects than in AMI subjects (p < 1,68 ´ 10-4 for RTm and p < 4,46 ´ 10-4 for RTe) and in CAD subjects (p < 3,23 ´ 10-5 for RTm and p < 0,02 for RTe). Breathing patterns affect the DERI index. In order to reduce that influence, we propose to record signals in periods with uniform breathing patterns, such as during sleep.

Palabras clave : MYOCARDIAL ISCHEMIA; RESEARCH; RESPIRATION; ELECTROCARDIOGRAPHY.