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Revista Cubana de Medicina

versión impresa ISSN 0034-7523versión On-line ISSN 1561-302X


GONZALEZ JIMENEZ, Noel; BAZAN MILIAN, Manuel; AROCHE APORTELA, Ronal  y  VALDES GARCIA, Maikel. Stem cell, an alternative to heart transplant in the treatment of heart failure. Rev cubana med [online]. 2005, vol.44, n.3-4. ISSN 0034-7523.

The traditional concept maintained for years on the incapacity of the adult heart to renew its cells had to be reviewed taking into account the results obtained by numerous studies that demonstrate the existence of cells with proliferative capacity in the human heart. Although the heart transplant has proved to be the definitive solution for heart failure, it may not be applied to all patients due mainly to the deficit of donors. The therapeutic and surgical advances improve the quality of life, but they cannot enhance the myocardial contractility, or replace the cardiomyocite. The cellular therapy in the myocardial regeneration appears as one of the strategical therapeutics with a promising future in the treatment of heart failure, even though it is not exempt from controversies that oblige to have a greater knowledge about its clinical application, but do not impede to start making clinical trials that allow to advance in this direction.

Palabras clave : Stem cells; myoblasts; heart regeneration; heart failure; heart transplant.

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