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Revista Cubana de Medicina

versão impressa ISSN 0034-7523versão On-line ISSN 1561-302X


GUERRA ALFONSO, Tamara et al. Histiocytic necrotizing lymphadenitis or Kikuchi-Fujimoti disease: Apropos of two observations. Rev cubana med [online]. 2007, vol.46, n.1. ISSN 0034-7523.

Histiocytic necrotizing lymphadenitis or Kikuchi-Fujimoti disease is a rare benign process. Two cases diagnosed with little time of appearance between one and other were presented. The first one was a 26-year-old white female with asthenia, weight loss, night sweating, chills, generalized pruritus and anorexia. On the physical examination, it was proved the presence of adenopathies, and nothing signficant was found in the lab tests. Various small ganglionar structures with partial preservation of the citoarchitecture and mild hyperplastic changes were observed. The second patient, a 34-year-old black male, presented morning fever, chills, odynophagia, headache and articular pain. It was deteced a reddened oropharynx with increase of the size of the tonsills , without exudates and adenopathies on the right lateral chain of the neck and submaxilla . No abnormal result was reported in the lab studies. In the histological examination of the ganglion, it was observed a nearly total preservation of its architecture, with hyperplastic cortical and paracortical changes. A spontaneous clinical remission was noticed in both patients.

Palavras-chave : Lymphadenitis; adenopathies; causes; Kikuchi disease..

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