Revista Cubana de Medicina
On-line version ISSN 1561-302X
LEON ALVAREZ, Jorge Luis et al. Value of serum ferritin for the diagnosis of adult Still's disease. Rev cubana med [online]. 2008, vol.47, n.3, pp. 0-0. ISSN 1561-302X.
Adult Still's disease is a rare systemic inflammatory disease of unknown etiology. It is characterized by high fever, arthritis, neutrophilic leukocytosis and evanescent exanthema. The values of serum ferritin over 3 000 ng/mL are very useful to establish the diagnosis. A 25-year-old patient with adult Still's disease that presented prolonged fever, rash, odinophagia and arthritis was presented. The existence of leukocytosis, hypertransaminemia, very elevated serum ferritin, antinuclear antibodies and negative rheumatoid factors was confirmed by complementary tests. The symptoms disappeared on administering indomethacin. It was concluded that the high levels of serum ferritin have a great value to diagnose active adult Still's disease and that its reduction is correlated with the favorable evolution of the clinical picture.
Keywords : Adult Still's disease; serum ferritin; rheumatoid factor; non-steroidal antiinflammatories; prednisone.