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Revista Cubana de Medicina
versão On-line ISSN 1561-302X
Resumo
GOMEZ PADRON, María Virginia e GOMEZ PADRON, Enrique Ivo. Cardiovascular disorders in patients with HIV infection. Rev cubana med [online]. 2010, vol.49, n.3, pp. 268-274. ISSN 1561-302X.
This paper is a bibliographic revision of the possible mechanisms of heart disease generation in HIV positive and AIDS patients, which concluded that HIV could be considered as a viral infection capable of generating risk of heart disease at the level of the valvular and mural endocardium and triggering the onset of endocarditis. The myocardium is one of the cardiac structures most frequently affected by the emergence of interstitial myocarditis, dilated cardiomyopathy, cardiac neoplasms such as Kaposi's sarcoma and immunoblastic B-cell lymphoma. Of all cardiac structures, the most frequently affected, according to autopsy studies, is the pericardium, with the presence of acute pericarditis; mild, moderate and severe pericardial effusion; cardiac tamponade and constrictive pericarditis. Finally, the development of coronary atherosclerosis secondary to hyperlipidemia has been observed at the level of the coronary endothelium, which is attributed to the introduction of antiretroviral treatment leading to the emergence of a metabolic syndrome, which could cause coronary endothelial dysfunction.
Palavras-chave : HIV; AIDS; dilated cardiomyopathy; pericardial effusion; myocarditis; pericarditis.