Revista Cubana de Medicina
On-line version ISSN 1561-302X
PEREZ RODRIGUEZ, Alexis et al. Superior digestive tract alterations and infection by Helicobacter pylori in renal transplant patient. Rev cubana med [online]. 2011, vol.50, n.2, pp. 179-189. ISSN 1561-302X.
A retrospective, observational and cohort study was conducted in all patients underwent renal transplantation carried out in the Institute of Nephrology between August, 2003 and August, 2007 to determine the prevalence and incidence of Helicobacter pylori infection, the associated superior digestive tract alterations and the response to treatment. A gastroduodenoscopy with urease test was prescribed for the diagnosis of associated digestive alterations H.pylori during the first month from transplantation repeating the study at 6 months, at one year and between the 2 and 5 years post-transplantation. There was an infection prevalence of 44.62 %, with a similar distribution in the different age groups; prevalence was great in male sex and in white race. The incidence found was of 16.67 % and a great frequency among the 30 and 39 years old, in white race and without differences between both sexes. The significant digestive alterations associated with the infection were the erythematous gastritis and the duodenal ulcer. All patients presenting with infection were treated con a triple therapy, metronidazole, amoxicillin and ranitidine during 15 days. There was cure in all patients and in only two patients the associated digestive alterations not to be resolved with treatment. We conclude that there is a high incidence of Helicobacter pylori infection incidence in patients underwent transplantation in the Institute of Nephrology, infection is associated with an erythematous gastritis and duodenal ulcer and the response to treatment is good in patients with renal transplantation.
Keywords : Renal transplantation; Helicobacter pylori.