SciELO - Scientific Electronic Library Online

 
vol.57 número3Desmielinización osmótica pontina y extrapontina durante un puerperio complicadoInfarto isquémico mesencefálico: síndrome de Weber índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

  • Não possue artigos citadosCitado por SciELO

Links relacionados

  • Não possue artigos similaresSimilares em SciELO

Compartilhar


Revista Cubana de Medicina

versão impressa ISSN 0034-7523versão On-line ISSN 1561-302X

Resumo

ARGUELLES ZAYA, Ana; INFANTE AMOROS, Adalberto; CHONG LOPEZ, Agustín  e  CHAO PEREIRA, Caridad. IgG4-related disease. Rev cubana med [online]. 2018, vol.57, n.3, pp.38-42. ISSN 0034-7523.

IgG4 - related disease is characterized by inflammatory fibrosis accompanied by elevated IgG4 serum concentrations. Clinically it can show involvement of one or multiple organs. It has been considered that this disease is secondary to the interaction between Th2 cells and B cells, which results in high concentrations of IgG4 and inflammatory mediators subsequent to lymphoplasmacytic infiltrates and fibrosis. However, it is not the only mechanism involved. For the diagnosis, clinical, serological, histopathological and immunohistochemical criteria are required. Good response to steroid treatment has been observed. We report the case of a 30-year-old woman with recurrent pleural effusion, interstitial lung disease, impaired progressive renal function, and elevation of parathyroid hormone and calcium in the blood. The studies revealed high serum levels of IgG4, lung and kidney biopsy consistent with IgG4-related disease. The patient was treated with 40 mg prednisone a day with excellent response.

Palavras-chave : IgG4; fibrosis; IgG4-related disease.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons