Introduction:

Fever of unknown origin is a syndrome that generates great challenge for clinical thought; the recurrent pattern is the most challenging subtype and with difficult etiological diagnosis.

Objective:

To describe patients with fever of unknown origin with recurring pattern.

Method:

A descriptive cross-sectional study was carried out from January 2008 to December 2015. Forty-eight patients formed the sample. They were hospitalized and underwent clinical evaluation at "Hermanos Amejeiras" Surgical Clinical Hospital. For data analysis, summary measures were used for qualitative variables and mean and standard deviation variables were used for quantitative.

Results:

The mean age was 41.3 years, men predominated (62.5 %), the mean duration of fever was 497 days, and the most important clinical signs were the findings of lymphadenopathy (43.8 %) and hepatomegaly. (22.9 %). Undiagnosed cases were 45.8 %.

Conclusions:

Fever of unknown origin with recurring pattern is difficult to diagnose. Despite careful clinical evaluation, most patients remain undiagnosed.

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