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Revista Cubana de Medicina

versión impresa ISSN 0034-7523versión On-line ISSN 1561-302X


ARGUELLES ZAYAS, Ana del Carmen; CHICO CAPOTE, Aracelis; KOKUINA, Elena  y  CASAS FIGUEREDO, Nelsas. Clinical and immunological characteristics and organ damage in patients with idiopathic inflammatory myopathies. Rev cubana med [online]. 2021, vol.60, n.2, e1345.  Epub 01-Jun-2021. ISSN 0034-7523.


Idiopathic inflammatory myopathies constitute a group of muscle diseases characterized by chronic muscle weakness and muscle inflammation of unknown etiology.


To identify the clinical and immunological characteristics and organ damage in patients with idiopathic inflammatory myopathies.


An observational, descriptive, cross-sectional study was carried out in 52 patients with diagnosis of idiopathic inflammatory myopathy, followed up in the protocolized service of Rheumatology at Hermanos Ameijeiras Clinical Surgical Hospital from January 2016 to January 2017. The qualitative variables were calculated with the percentages in each group. Pearson's Chi-square (Fisher's exact statistic) (95% significance level (α = 0.05) was used to relate the presence of antibodies and the type of myopathy as well as the presence of clinical manifestations of idiopathic inflammatory myopathies.


80.8% were women of the total patients studied, 61.5% non-white skin color, 86.5% of urban origin. The mean age at the beginning was 42.8 ± 13.2 years, time delay to diagnosis was 8.8 ± 7.0 months, mean time of evolution of the disease of 7.5 ± 7.1 years. 80.8% were in remission, 50% had specific antibodies. Hypertension was found in 28.8% of the patients and 23.1% had interstitial pneumonia. Arthritis was present in 96.2%. We found 26.9% had specific Jo1 antibodies and 21.2% Ro 52.


Urban origin female patients predominated, in their fourth decade of life, the more frequent specific antibodies found was anti Jo-1, which was associated with the presence of interstitial lung disease.

Palabras clave : idiopathic inflammatory myopathy; Jo1 and Ro 52 specific antibodies; dermatomyositis; polymyositis.

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