SciELO - Scientific Electronic Library Online

vol.60 suppl.1Pielonefritis enfisematosaQuiste enterogénico y agenesia renal en la edad adulta índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados




  • Não possue artigos citadosCitado por SciELO

Links relacionados

  • Não possue artigos similaresSimilares em SciELO


Revista Cubana de Medicina

versão impressa ISSN 0034-7523versão On-line ISSN 1561-302X


ORTEGA ROSALES, Alberto; ROMERO ULLOA, Gilda  e  BURNEO ROSALES, Carlos. Toxic megacolon in a patient with Covid-19. Rev cubana med [online]. 2021, vol.60, suppl.1, e2484.  Epub 01-Dez-2021. ISSN 0034-7523.


The pandemic derived from the 2019 novel coronavirus disease (COVID-19) has become a global public health emergency, due to the fact that it can develop life-threatening complications. Although SARS-CoV-2 is known to cause substantial lung disease, many extra-pulmonary manifestations have been observed, including involvement of the gastrointestinal system. Toxic mega colon is a rare but life-threatening complication most associated with inflammatory bowel disease. However, any condition that leads to inflammation of the colon can lead to toxic dilation.


To report the case of a patient with ARDS secondary to a SARS-COV-2 infection. Concomitantly, she had non-obstructive dilation of the colon, associated with systemic toxicity.

Clinical case report: The development of toxic mega colon in a patient with SARS-COV-2 may be justified because the virus infects host cells through the angiotensin-converting enzyme 2 receptor. The diagnostic criteria for toxic megacolon were met.


It is also highly expressed in intestinal epithelial cells, therefore, its timely diagnosis should be considered for early intervention, in order to reduce the mortality rate as much as possible.

Palavras-chave : COVID-19; angiotensin converting enzyme 2; gastrointestinal manifestations; toxic megacolon.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )