Abstract

MARTI CASTELLO, Eloísa et al. Correlación clinico-microbiológica en 9 pacientes con fibrosis quística. Rev Cubana Pediatr [online]. 1996, vol.68, n.2, pp.91-98. ISSN 0034-7531.

Among patients suffering from cystic fibrosis the Pseudomonas aeruginosa is the most important pathogen as a cause of chronic pulmonary infection and it has been proved that lung inflammatory response may contribute to the pathogenesis of this infection, with the participation of specific and unspecific defence mechanisms. Therefore, clinical and microbiological manifestations are correlated in 9 patients with cystic fibrosis. Patients were diagnosed by the clinic and electrolites in sweat and it was carried out a microbiological study of sputum or deep swab, where the Pseudomona aeruginosa was isolated in all cases. Antipseudomona aeruginosa antibodies in serum were determined and the results were connected with the clinic. Elevated titres were obtained in all patients in different determined serotypes and there was a relationship between antibody titres and clinical manifestations. A decrease of titres in patients treated with steroids or under antipseudomona treatment was also observed.

Keywords : PULMONARY FIBROSIS [microbiology]; CYSTIC FIBROSIS [microbiology]; PSEUDOMONAS AERUGINOSA [isolation and purification].