Revista Cubana de Pediatría
versão On-line ISSN 1561-3119
PENA BAZAIN, Nelson et al. Antifibrinolíticos: Uso en cirugía cardiovascular pediátrica. Rev Cubana Pediatr [online]. 2000, vol.72, n.1, pp. 47-53. ISSN 1561-3119.
Extracorporeal circulation technique (ECC), used routinely in pediatric cardiovascular surgery, in present time regarded as a safe procedure, however, involve serious hemobiological disturbances, with a high risk of bleedings and the need of blood transfusions. Prophylactic use of antifibrinolitic drugs (Y aminocaproic acid, traxenamic acid, and aprotinin) in theses procedures, seems to be useful to decrease blood losses and transfusion requirements. We made a review of this topic in cardio-pediatric surgery with the aim of search a reasoning of its use. Most of the published researches confirm effectiveness of antifibrinolitics given in a prophylactic way, but further studies will be neccesary to make definitive conclusions.
Palavras-chave : EXTRACORPORAL CIRCULATION; CARDIOVASCULAR SURGICAL PROCEDURES; ANTIFIBRINOLITIC AGENTS; PEDIATRICS.