Revista Cubana de Pediatría
versão On-line ISSN 1561-3119
Hyperlactatemia is a clinical problem for patients. The lactic acidosis is an acid-base disorder following the builup of lactic acid which at cellular level hehaves as a reduced counterpart of the pyruvic acid. The latter results from the degradation of glucose into citosol, a process that is anaerobically carried out and may end up in CO2 H2O if it takes the Krebs? citric acid route. The diagnosis sof this entity is confirmed by measuring blood lactate concentration although there are several clinical and lab characteristics that demonstrate the existance of this disorder. The causes of lactic acidosis are divided into those caused by hystic hypoxia (type A) and those not caused by this disorder (type B) such as lactic acidosis due to systemic disorders, use of drugs or toxins and acidosis resulting from inborn metabolic errors.
Palavras-chave : ACID-BASE IMBALANCE; ACIDOSIS,LACTIC [diagnosis]; ACIDOSIS, LACTIC [etiology]; ACIDOSIS, LACTIC [drug therapy]; CHILD.