SciELO - Scientific Electronic Library Online

 
vol.80 número1Shock séptico en pediatría: un acercamiento a su manejoLas trombosis senovenosas en la infancia: clínica, diagnóstico y tratamiento índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO

Compartir


Revista Cubana de Pediatría

versión impresa ISSN 0034-7531versión On-line ISSN 1561-3119

Resumen

LOPEZ PEREZ, Irma Rosa. Heredity in asthma . Rev Cubana Pediatr [online]. 2008, vol.80, n.1. ISSN 0034-7531.

Asthma is a complex disease associated with a high prevalence of allergy. Both, asthma and allergy are caused by complex interactions of the genoma with the environment. It is a challenge to investigate the bases of genetic susceptibility in asthma and atopy, since there are multiple genetic and environmental factors that interact to modulate their heterogeneous clinic expression. The expression of the disease is even more heterogeneous if we consider aspects such as severity, natural evolution or the response to treatment. We proposed to refer to those aspects related to heredity in asthma, taking into account the importance of interpreting this genetic participation in the understanding of the physiopathology underlying in the natural history of asthma, in its severity and in the response to treatment. This analysis will allow us to follow efficient therapeutic conducts from the very emergence of asthma.

Palabras clave : Asthma; heredity; complex disease; heterogeneous clinical expression; genetic polymorphism; susceptible genes; candidate genes.

        · resumen en Español     · texto en Español     · Español ( pdf )

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons