Revista Cubana de Pediatría
versão On-line ISSN 1561-3119
ROIG ALVAREZ, Tania. Infection caused by Candida species during the neonatal intensive care. Rev Cubana Pediatr [online]. 2008, vol.80, n.3, pp. 0-0. ISSN 1561-3119.
In Cuba, with the rise of the survival of newborn infants with a birth weight under 1500 g, the isolations of Candida species in the neonatal intensive care units may be increasingly frequent. To update the topics related to the world problems of neonatal infection due to Candida species, diagnostic criteria and therapeutic management, it was made a review directed mainly to Neonatology specialists. It was confirmed that the most isolated species in infants are Candida albicans, C. Glabrata, C. Parapsilosis, and C. Tropicalis. The clinical picture is not specific, and it may appear between the second and third weeks of life. The clinical laboratory findings are also equivocal. The accurate diagnosis is made by fungus isolation in sterile sites as blood, cerebrospinal fluid (CFS), pericardial fluid or by means of tissue biopsy. The first-line curative treatment against invasive candidiasis in newborn infants is still Amphotericin B. In these patients it is very important to remove deep vascular catheters when there are suspicions, and on confirming the infection.
Palavras-chave : Systemic candidiasis; candidemia; neonatal intensive care.