Resumen

DOMINGUEZ DIEPPA, Fernando; CEJAS PEREZ, Gianny; ROCA MOLINA, María del Carmen  y  MILLAN CRUZ, Yraida. Neurodevelopment of the first high frequency ventilated Cuban neonates. Rev Cubana Pediatr [online]. 2009, vol.81, n.4, pp. 42-52. ISSN 1561-3119.

INTRODUCTION: The objective of present study was to describe the neurodevelopment during the first 2 years of life of the first Cuban newborns underwent high frequency ventilation (HFV) in oscillatory modality. METHODS: A longitudinal and descriptive study was conducted in 19 newborns treated with HFV and the final assessment of neurodevelopment was related to some perinatal variables and to the ventilation type. RESULTS: There were neonates (21%) presenting with neurodevelopment alterations. Course was normal in all those weighing less than 2000 g at birth, and in the 40% of the series weighing 2500 or more. There were alterations in the 13% of pre-term neonates and in the 50% of at-term births, as well as a slight predominance of normality in male sex (82% versus 75%). There was only one patient with a low and a sustained Apgar score from the 4 with sequelae. Neurodevelopment course was normal in 89% of those underwent to high frequency ventilation during 8 hours or more; in 30% we found alterations from those underwent to ventilation during less than 48 hours. Almost all the neonates underwent to ventilation during more than 96 hours, including those presenting sequelae. CONCLUSIONS: The fifth part of newborns underwent high frequency ventilation had neurodevelopment sequelae during the first 2 years of life with a predominance of the moderate ones. This ventilation modality by itself was not associated with a higher sequelae incidence, which were more frequent in neonates with higher weight and gestational age. With less time in high frequency and a total higher time in ventilation therapy, greater was the incidence of neurodevelopment alterations.

Palabras clave : Neurodevelopment; high frequency ventilation; neonatal respiratory assistance; neonatal ventilation; neonate; newborn.

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