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Revista Cubana de Pediatría

versión On-line ISSN 1561-3119


RAMIREZ PEREZ, Carlos et al. Congenital chlorhydria:: first report in Cuba. Rev Cubana Pediatr [online]. 2009, vol.81, n.4, pp. 86-92. ISSN 1561-3119.

In present paper are showed the prenatal, perinatal and postnatal backgrounds from a male breast-fed baby aged 6 months presenting with congenital chlorhydria, as well as the clinical picture, diagnosis and treatment applied. A significant element was the anal expulsion of non-meconium abundant fluid from the first hours of born, as well as a severe metabolic alkalosis and the presence of a quickly progressive malnutrition. In complementary examinations was confirmed a 50% hypochloremia regarding the reference figures and a blood pH over 7,50. Confirmatory diagnosis was achieved verifying the chlorine concentrations in feces higher to that of the sum of sodium and potassium. Prenatal diagnostic indicators are proposed those with higher value including the consanguinity, polyhydramnios and the US results during the third trimester of pregnancy. Early diagnosis allowed us to establish the treatment and to prevent a fatal outcome. This is the firs case of this entity reported in our country.

Palabras clave : Congenital chlorhydria; metabolic alkalosis; hypochloremia.

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