Revista Cubana de Pediatría
versão On-line ISSN 1561-3119
ALERT SILVA, José; CABALLERO AGUIRRECHU, Iraida; RENO CESPEDES, Jesús e PEREZ PENA, Lourdes. Nasopharyngeal juvenile angiofribroma:: updating of radiotherapy results. Rev Cubana Pediatr [online]. 2010, vol.82, n.1, pp. 0-0. ISSN 1561-3119.
INTRODUCTION: The nasopharyngeal juvenile angiofribroma is a uncommon benign tumor composed of fibrous connective tissue and many vascular spaces covered by endothelium. It is almost exclusive of male sex and of adolescents. Choice treatment is the exeresis without obviate other possibilities as the radiotherapy. The aim of present study was to show the results of this latter as therapeutical option. METHODS: Authors studied a series of 11 male patients, aged between 9 and 16, seen in National Institute of Oncology and Radiobiology of La Habana between1990 and 2005. Patients were followed during 48 and 306 months. Radiotherapy applied was the irradiation of all the tumor volume with a accuracy margin in dose of 40 and 60 Gy, with 1,8 Gy by session. Together with radiotherapy we used Interferon, during and after irradiation and polychemotherapy in one patient. RESULTS: There was a maintained complete remission without relapses in 10 patients. There weren't patients with a second tumor. All patients had early complications and late in some of them. Among the early complications we found radiomucositis and radiogenic conjunctivitis and the more severe of the late complications were the permanent loss of eyelash of lower eyelid in a case and radiogenic cataract in 4 patients. CONCLUSIONS: Radiotherapy is a treatment maintaining its usefulness and specific indications.
Palavras-chave : Juvenile angiofibroma; nasopharynx; radiotherapy; complications.