Revista Cubana de Pediatría
versión On-line ISSN 1561-3119
OQUENDO DE LA CRUZ, Yudalvis; PINEIRO LAMAS, Regino; DUARTE, María Caridad y GUILLEN DOSAL, Ana. Metabolic syndrome in hypertensive and obese children and adolescents. Rev Cubana Pediatr [online]. 2010, vol.82, n.4, pp. 31-40. ISSN 1561-3119.
INTRODUCTION. The combination of high blood pressure and obesity in childhood increases the risk of metabolic syndrome (MS) in early ages of life. The aim of present study was to determine the presence of MS in obese hypertensive adolescents and its relation to some clinical and biochemical variants. METHODS. A prospective and descriptive study was conducted in 152 obese children and adolescents aged 5 and 19 from the Nephrology consultation of the "Juan Manuel Márquez" University Children Hospital and also authors studied the fasting microalbuminuria, glycemia, total cholesterol and triglycerides. RESULTS. There was metabolic syndrome in the 35.5% of obese hypertensive and it was more frequent in male sex. There was predominance of severe obesity and 8 of each 10 children had three criteria of the syndrome. The prevalence of each of components was of 33.3% in glucose metabolism alteration, of 100% in central obesity and high blood pressure, of 51.8% in hypertriglyceridemia, and of 13% in high density lipoprotein low cholesterol (HDL-C). Almost half of patients had microalbuminuria. The 31.5% of study subjects had insulin-resistance and in the 29.5% of cases there was non-alcoholic fatty liver. CONCLUSIONS. One of each 3 obese hypertensive patient had metabolic syndrome, thus, it is recommended to continue research on this syndrome in childhood and adulthood.
Palabras llave : Metabolic syndrome; obesity; high blood pressure.