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Revista Cubana de Pediatría

versão impressa ISSN 0034-7531

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CAMPANA COBAS, Neri Georgina et al. First case of C1q nephropathy in Cuba. Rev Cubana Pediatr [online]. 2013, vol.85, n.2, pp. 258-264. ISSN 0034-7531.

C1q nephropathy is a poorly understood glomerulopathy with some conceptual controversies, but with a distinctive immunologic characteristic (dominant or co-dominant deposit of C1q) and neither clinical nor serological evidence of systemic erythematous lupus. This is the case of a male patient who began suffering nephritic syndrome with hematuria, blood hypertension and renal failure at 10 months of age. A first renal biopsy was performed to detect diffuse mesangeal sclerosis; however after partial response of the patient to prednisone therapy and to maintenance treatment of proteinuria in nephritic range, with normalization of humoral parameters, then a second renal biopsy was performed with immunofluorescence. The final result was C1q nephropathy.

Palavras-chave : nephrotic syndrome; C1q nephropathy; hematuria; proteinuria.

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