Abstract

ZAMORA LINARES, Carlos Evaristo. Some factors related to heredity in children with cleft lip and palate. Rev Cubana Pediatr [online]. 2014, vol.86, n.4, pp.454-461. ISSN 0034-7531.

Objective: to describe and to evaluate some characteristics of the hereditary factor in a population with cleft lip and palate. Methods: descriptive and analytical research that uses the field study and ethnography. From 1986 to 2013, one hundred and forty two children with cleft lip and palate were attended to in "Hermanos Cordove" hospital in Manzanillo, Gramma province, Cuba. Forty five of them had family histories of malformations. A set of data on the selected variables was collected through the clinical exam and the interview, the information was physically confirmed and through testimony comparisons, and then processed by means of frequency summary and association data. The inter-variant independence hypothesis was estimated using the Chi-square test whereas the association according to the ratio rate and its confidence intervals was 95 %. Results: in the study, 31.7 % of patients had a family history in which the maternal progeny (58 %), the second kindship (50.9 %) and the male patients (73.5 %) were predominant. Conclusions: neither the family history nor the affected progeny seem to have influence over the type of cleft lip. Male sex and complex fissures were related to higher risk of relapse.

Keywords : cleft lip and palate; malformation; heredity; relapse; children.

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