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Revista Cubana de Pediatría
versión On-line ISSN 1561-3119
Resumen
LINARES-PEREZ, Nivaldo et al. New Cuban pneumococcal vaccine, from available scientific evidence to the strategy of clinical and impact evaluation. Rev Cubana Pediatr [online]. 2017, vol.89, suppl.1, pp. 181-196. ISSN 1561-3119.
This paper summarized the group of evidence that supports the present use of the pneumococcal conjugate vaccines in terms of safety, immunogenicity, efficacy and effectiveness. It offers a new alternative to prevent the pneumococcal disease in the infant population on the basis of a new Cuban vaccinal candidate against pneumococci. It set out the basic principles that define the strategy for the introduction of this vaccine in Cuba and the advances resulting from the use of an integrated model for the clinical evaluation and the impact on health, in its implementation phase, which seeks to provide the scientific evidence backing up the decision of the national health care system to introduce this vaccine in the national immunization schedule and its further commercialization in the era of pneumococcal conjugate vaccines. Preliminary results of finished studies were presented and the conclusions on the scientific and practical contributions of the strategy of implementation and the evaluation model for the new vaccine were worked out.
Palabras clave : Streptococcus pneumoniae; evaluation; evidence; pneumococcal conjugate vaccines; Cuba.