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Revista Cubana de Pediatría

versão impressa ISSN 0034-7531versão On-line ISSN 1561-3119


CONSUEGRA OTERO, Araíz; MARTINEZ TORRES, Eric; GONZALEZ RUBIO, Daniel  e  CASTRO PERAZA, Marta. Clinical and laboratory characterization in pediatric patients at the critical stage of dengue. Rev Cubana Pediatr [online]. 2019, vol.91, n.2, e645. ISSN 0034-7531.


Dengue is an acute infectious disease transmitted by Aedes aegypti mosquito, which can be of varying intensity and it mainly affects the children population.


To describe clinical and laboratory manifestations in the critical phase of dengue in children of one year or more.


A cross-sectional study was performed with an analytical component. 195 patients diagnosed with dengue infection and admitted to the intensive care unit of the Pediatric Teaching Hospital of Cerro were studied from January to December 2013. The results were expressed in absolute and relative frequencies, and range. For the analysis of the relationship between the different symptoms and clinical signs, the chi-square test was applied, with significant p-values of < 0.005.


Warning signs that appeared more frequently were abdominal pain vomiting and vaginal bleeding in female adolescents. Most of them classified as non-severe dengue with warning signs. No death was caused by this.


The clinical presentation of dengue in the examined pediatric patients corroborates that there are general symptoms and signs, as well as signs of alarm that characterize the disease. However, laboratory tests do not support the clinical evidences of the disease. The prevalence of the various severe types of dengue was low, which points towards a relationship between early clinical management and satisfactory evolution, and suggests that the clinical method constitutes an effective tool for decision-making.

Palavras-chave : dengue; warning signs; severe dengue..

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