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Revista Cubana de Pediatría

Print version ISSN 0034-7531On-line version ISSN 1561-3119

Abstract

GARCIA GARCIA, Ramiro Jorge  and  SANCHEZ DOMINGUEZ, Mario Antonio. Acute symptomatic crisis and epilepsy in children and adolescents in times of COVID-19. Rev Cubana Pediatr [online]. 2020, vol.92, suppl.1, e1182.  Epub July 20, 2020. ISSN 0034-7531.

Objective:

To describe the most outstanding aspects in children and adolescents with acute symptomatic crisis or diagnosis of epilepsy in times of the COVID-19 pandemic.

Methods:

The information was collected in PubMed/Medline, Scielo and Clinical Key databases using the keywords included in the Descriptor of Health Sciences in English or Spanish language, with not time limit, and looking for all kind of publications. There were selected articles related to epilepsy, epileptic seizures and COVID-19.

Results:

In the consulted literature, it was justified the occurrence of epileptic seizures due to different causes in patients with COVID-19 and it is highlighted the therapeutic behaviour and the need of surveillance of the pharmacologic interactions among the drugs indicated for the prevention of epileptic seizures and the specific of this new disease. Based in these precepts, we present a final proposal for the behaviour to follow in each situation.

Final considerations:

It is proved the possibility of neurologic complications in patients with COVID-19 and specifically in the epileptic seizures and epilepsy. The use of interferon and lopinavir/ritonavir, in case of being indicated in the action protocols, and to keep the previous treatment with the drugs to prevent the recurrence of crisis in epileptic patients considering the possible interactions and the required surveillance in each case, seems to be the best option in most of the children and adolescents with COVID-19.

Keywords : Infections by coronavirus; epilepsy; convulsions; pharmacological interactions; COVID-19.

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