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Revista Cubana de Pediatría

Print version ISSN 0034-7531On-line version ISSN 1561-3119

Abstract

ACOSTA TORRES, José; ACOSTA BATISTA, Bárbara; PEREZ CUTINO, Maité  and  RODRIGUEZ PRIETO, Magela. Infection by SARS-CoV-2 virus and its consequences in pregnant women and newborns. Rev Cubana Pediatr [online]. 2020, vol.92, suppl.1, e1189.  Epub Feb 22, 2020. ISSN 0034-7531.

Introduction:

The infection by SARS-CoV-2 that produces COVID-19 disease is considered a zoonoses. This has generated the current pandemic that expands its effects to the expectant mothers and newborns population.

Objective:

To update the available knowledge on the infection by SARS-CoV-2 virus and its consequences in pregnant women and newborns.

Methods:

There were identified articles in PubMed database and Google Scholar platform on the topic above mentioned and series of cases reports and laboratory data that were published until May 31st, 2020.

Results:

Newborns of mothers infected with SARS-CoV-2 have no specific kind of clinical or laboratory profile, and the mother´s exposure to the virus in the first quarter of pregnancy can be an important indicator of severe complications in the future baby. It has not been proven vertical transmission and there is contradiction with the use of breastfeeding.

Final considerations:

According to some researches, intrauterine exposure to SARS-CoV-2 virus does not represent a serious threat to the development of the cellular and humoral immune response´s function in newborns; but it does confirm that maternal infection, mainly in the first quarter of pregnancy, can be an important indicator of severe complications in the newborn.

Keywords : Coronavirus; SARS-CoV-2; COVID-19; immunity; cytokines.

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