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Revista Cubana de Pediatría

versión impresa ISSN 0034-7531versión On-line ISSN 1561-3119


NODA ALBELO, Amauri Lázaro et al. Microangiopathic anemia and multisystem inflammatory syndrome associated to COVID-19 in a Cuban pediatric patient. Rev Cubana Pediatr [online]. 2020, vol.92, suppl.1, e1253.  Epub 30-Nov-2020. ISSN 0034-7531.


Clinical manifestations of the infection by SARS-CoV-2 are less frequent and severe in children than in adults; however, recent publications suggest the possibility of a severe clinical scenario secondary to the infection by this coronavirus called multisystem inflammatory syndrome in children (MIS-C). This syndrome has a post-infection nature and its physiopathology is probably the result of an abnormally organized activation of the immune system in a genetic context of predispostion, and actived by the particular biology of SARS-CoV-2.


To describe the first Cuban case with criterion of multisystemic syndrome associated to COVID-19.

Case presentation:

2 years old male patient, previously healthy, with clinical and laboratory evidences of microangiopathic anemia, systemic hyperinflammation and organs and systems´ multiple dysfunction, associated with serologic evidences of previous infection by SARS-CoV-2.


The proper approach to cases as the above mentioned in this work requires to keep a high level of clinical alert, with a clear definition of suspicious cases, multidisciplinary participation and the early establishment of and adequate therapeutic strategy that will be significant in the reduction of systems and organs damage´s extension; as well as increasing the chance to improve the dysfunction.

Palabras clave : SARS-CoV-2; COVID-19; multisystem inflammatory syndrome; shock; microangiopathic anemia.

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