Introduction:

Pigment incontinence is a systemic neuroectodermal disorder that in the newborn is diagnosed by the presence of skin lesions of erythematous-vesiculosus or vesicle-pustulous type, with distribution according to the Blaschko lines, associated with eosinophilia in the blood sample.

Objective:

Show that it is feasible to diagnose pigment incontinence in the neonatal period, even in sporadic cases, through proper performance of the clinical method.

Presentation of cases:

These are two female newborns, born full-term, with a suitable weight for gestational age and without a pre- and perinatal history of interest; the first case occurs on the third day of life, presenting skin lesions, vesicle-pustulous in appearance, which followed the path of the external popliteal sciatic nerve. The second case occurs on the 11th day of life with vesicle-ampulose lesions in the outer region of the four limbs, with improvement at 26 days of life. Diagnosis of sporadic pigment incontinence is stated in both cases.

Conclusions:

Diagnosing pigment incontinence in the neonatal period is a challenge, which can be assumed if proper use of the clinical method is carried out, with a thorough differential diagnosis.

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