Introduction:

Kawasaki disease is the main cause of heart disease acquired in childhood, however, its diagnosis is difficult after the onset of SARS-CoV-2.

Objective:

To examine a case with incomplete Kawasaki disease in the context of the COVID-19 pandemic and the diagnostic challenge it represents.

Case presentation:

A 5-month-old female patient brought by her parents to the emergency service due to upper respiratory symptoms and multiple emetic episodes. During her hospitalization, she presented fever that was difficult to control, edema in the extremities, polymorphous exanthema and a strawberry tongue, so after ruling out the pediatric multisystem inflammatory syndrome temporarily associated with COVID 19, Kawasaki disease was diagnosed. Treatment with intravenous immunoglobulin and acetylsalicylic acid is indicated. The patient progressed satisfactorily and was discharged on day 10 of hospitalization.

Conclusions:

The differentiation of Kawasaki disease with pediatric multisystem inflammatory syndrome is vital, given that the latter presents a higher risk of morbidity and mortality in the short term.

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